Cloud native, service-meshed Java Enterprise with Istio

In enterprise software, we see more and more of the cloud native technologies, especially container orchestration and service meshes, emerging and slowly taking over the market. Developers are facing the challenge which technology to choose to implement microservices for a cloud native setting. Java Enterprise has been used for software solutions for a long time and its APIs are well-established in the ecosystem. However, is it possible to develop cloud native, service-meshed Java Enterprise applications that fulfill concerns such as scalability, resiliency, and telemetry — in an effective, manageable way?